Semmelweis Publications
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    • Ambrus, Attila Semmelweis University affiliated publications (2021-2026)

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    Number of publications: 10
    1.
    Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implications for the overall hKGDHc structure
    Nagy, B;Polak, M;Ozohanics, O;Zambo, Z;Szabo, E;Hubert, A;Jordan, F;Novacek, J;Adam-Vizi, V;Ambrus, A
    Q1
    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
    2021.
    DOI:10.1016/j.bbagen.2021.129889 (Copy DOI)
    2.
    Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency
    Piroli, GG;Manuel, AM;Mccain, RS;Smith, HH;Ozohanics, O;Mellid, S;Cox, JH;Cotham, WE;Walla, MD;Cascón, A;Ambrus, A;Frizzell, N
    D1
    REDOX BIOLOGY
    2023.
    DOI:10.1016/j.redox.2023.102932 (Copy DOI)
    3.
    Reverse and Forward Electron Flow-Induced H2O2 Formation Is Decreased in α-Ketoglutarate Dehydrogenase (α-KGDH) Subunit (E2 or E3) Heterozygote Knock Out Animals
    Horvath, G;Svab, G;Komlódi, T;Ravasz, D;Kacsó, G;Doczi, J;Chinopoulos, C;Ambrus, A;Tretter, L
    D1
    ANTIOXIDANTS
    2022.
    DOI:10.3390/antiox11081487 (Copy DOI)
    4.
    Functional Versatility of the Human 2-Oxoadipate Dehydrogenase in the L-Lysine Degradation Pathway toward Its Non-Cognate Substrate 2-Oxopimelic Acid
    Nemeria, NS;Nagy, B;Sanchez, R;Zhang, X;Leandro, J;Ambrus, A;Houten, SM;Jordan, F
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2022.
    DOI:10.3390/ijms23158213 (Copy DOI)
    5.
    Probing the E1o-E2o and E1a-E2o Interactions in Binary Subcomplexes of the Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Complexes by Chemical Cross-Linking Mass Spectrometry and Molecular Dynamics Simulation
    Ozohanics, O;Zhang, X;Nemeria, NS;Ambrus, A;Jordan, F
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2023.
    DOI:10.3390/ijms24054555 (Copy DOI)
    6.
    Methylene Blue Bridges the Inhibition and Produces Unusual Respiratory Changes in Complex III-Inhibited Mitochondria. Studies on Rats, Mice and Guinea Pigs
    Sváb, G;Kokas, M;Sipos, I;Ambrus, A;Tretter, L
    Q1
    ANTIOXIDANTS
    2021.
    DOI:10.3390/antiox10020305 (Copy DOI)
    7.
    Microgliosis, neuronal death, minor behavioral abnormalities and reduced endurance performance in alpha-ketoglutarate dehydrogenase complex deficient mice
    Kokas, M;Budai, A;Kádár, A;Mozaffaritabar, S;Zhou, L;Téglás, T;Orova, RS;Gáspár, D;Németh, K;Toth, DM;Sayour, N;Kovácsházi, C;Xue, AD;Szatmári, RZ;Törocsik, B;Máthé, D;Kovács, N;Szigeti, K;Nagy, P;Szatmári, I;Fekete, C;Arányi, T;Varga, ZV;Ferdinandy, P;Radák, Z;Kozlov, A;Tretter, L;Komlódi, T;Ambrus, A
    D1
    REDOX BIOLOGY
    2025.
    DOI:10.1016/j.redox.2025.103743 (Copy DOI)
    Semmelweis University authors: Kokas, Márton, Budai, András, Kádár, Andrea, Orova, Rebeka Sára, Németh , Kristóf, Tóth, Dániel Márton, Sayour, Viktor Nabil, Kovácsházi, Csenger, Xue, Andrea, Törőcsik, Beáta, Máthé, Domokos, Stelczerné Kovács, Noémi, Szigeti, Krisztián, Nagy, Péter, Szatmári, Ildikó, Arányi, Tamás, Varga, Zoltán, Ferdinandy, Péter, Radák, Zsolt, Tretter, László, Komlódi, Tímea, Ambrus, Attila,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Departmnet of Biophysics and Radiation Biology, Biokémiai és Molekuláris Biológiai Intézet, Biokémiai Tanszék, Molekuláris Biológiai Tanszék, Department of Pharmacology and Pharmacotherapy, Patológiai, Igazságügyi és Biztosítási Orvostani Intézet, Department of Pediatrics, Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket), Centre for Pharmacology and Pharmaceutical Research Development,
    8.
    Lipoamide dehydrogenase (LADH) deficiency: medical perspectives of the structural and functional characterization of LADH and its pathogenic variants
    Szabo, E;Ambrus, A
    Q2
    BIOLOGIA FUTURA
    2023.
    DOI:10.1007/s42977-023-00155-6 (Copy DOI)
    9.
    Structural and Biochemical Investigation of Selected Pathogenic Mutants of the Human Dihydrolipoamide Dehydrogenase
    Szabo, E;Nemes-Nikodem, E;Vass, KR;Zambo, Z;Zrupko, E;Torocsik, B;Ozohanics, O;Nagy, B;Ambrus, A
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2023.
    DOI:10.3390/ijms241310826 (Copy DOI)
    10.
    Mitochondrial Alpha-Keto Acid Dehydrogenase Complexes: Recent Developments on Structure and Function in Health and Disease
    Szabo, E.; Nagy, B.; Czajlik, A.; Komlodi, T.; Ozohanics, O.; Tretter, L.; Ambrus, A.;
    SUB-CELLULAR BIOCHEMISTRY 0306-0225 2542-8810
    2024.
    DOI:10.1007/978-3-031-58843-3_13 (Copy DOI)

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    Release: 2026_7
    Department data last refreshed at: 22.06.2026
    Author data last refreshed at: 22.06.2026
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