Central Library

1.

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

Alexander, SPH;Christopoulos, A;Davenport, AP;Kelly, E;Mathie, A;Peters, JA;Veale, EL;Armstrong, JF;Faccenda, E;Harding, SD;Pawson, AJ;Southan, C;Davies, JA;Abbracchio, MP;Alexander, W;Al-hosaini, K;Bäck, M;Barnes, NM;Bathgate, R;Beaulieu, JM;Bernstein, KE;Bettler, B;Birdsall, NJM;Blaho, V;Boulay, F;Bousquet, C;Bräuner-Osborne, H;Burnstock, G;Caló, G;Castaño, JP;Catt, K;Ceruti, S;Chazot, P;Chiang, N;Chini, B;Chun, J;Cianciulli, A;Civelli, O;Clapp, LH;Couture, R;Csaba, Z;Dahlgren, C;Dent, G;S...

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BRITISH JOURNAL OF PHARMACOLOGY

2021.

DOI:10.1111/bph.15538 (Copy DOI)

Semmelweis University authors: Hunyady, László,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology,

2.

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

Alexander, SPH;Christopoulos, A;Davenport, AP;Kelly, E;Mathie, AA;Peters, JA;Veale, EL;Armstrong, JF;Faccenda, E;Harding, SD;Davies, JA;Abbracchio, MP;Abraham, G;Agoulnik, A;Alexander, W;Al-hosaini, K;Bäck, M;Baker, JG;Barnes, NM;Bathgate, R;Beaulieu, JM;Beck-Sickinger, AG;Behrens, M;Bernstein, KE;Bettler, B;Birdsall, NJM;Blaho, V;Boulay, F;Bousquet, C;Bräuner-Osborne, H;Burnstock, G;Caló, G;Castaño, JP;Catt, KJ;Ceruti, S;Chazot, P;Chiang, N;Chini, B;Chun, J;Cianciulli, A;Civelli, O;Clapp, L...

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BRITISH JOURNAL OF PHARMACOLOGY

2023.

DOI:10.1111/bph.16177 (Copy DOI)

Semmelweis University authors: Hunyady, László,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology,

3.

Crowdsourced mapping of unexplored target space of kinase inhibitors

Cichonska, A;Ravikumar, B;Allaway, RJ;Wan, FP;Park, S;Isayev, O;Li, SY;Mason, M;Lamb, A;Tanoli, Z;Jeon, M;Kim, S;Popova, M;Capuzzi, S;Zeng, JY;Dang, K;Koytiger, G;Kang, J;Wells, CI;Willson, TM;Oprea, TI;Schlessinger, A;Drewry, DH;Stolovitzky, G;Wennerberg, K;Guinney, J;Aittokallio, T;Tan, M;Huang, CH;Shih, ESC;Chen, TM;Wu, CH;Fang, WQ;Chen, JY;Hwang, MJ;Wang, XK;Ben Guebila, M;Shamsaei, B;Singh, S;Nguyen, T;Karimi, M;Wu, D;Wang, ZY;Shen, Y;Öztürk, H;Ozkirimli, E;Özgür, A;Lim, H;Xie, L;Kanev,...

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NATURE COMMUNICATIONS

2021.

DOI:10.1038/s41467-021-23165-1 (Copy DOI)

Semmelweis University authors: Turu, Gábor, Misák, Ádám, Szalai, Bence, Hunyady, László,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology,

4.

Effect of hormone-induced plasma membrane phosphatidylinositol 4,5-bisphosphate depletion on receptor endocytosis suggests the importance of local regulation in phosphoinositide signaling

Tóth, DJ;Tóth, JT;Damouni, A;Hunyady, L;Várnai, P

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SCIENTIFIC REPORTS

2024.

DOI:10.1038/s41598-023-50732-x (Copy DOI)

Semmelweis University authors: Tóth, Dániel, Tóth, József, Damouni, Amir, Hunyady, László, Várnai, Péter,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Intensive Care Clinic, Department of Anesthesoiology and Intensiv Therapy,

5.

PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells

Prokop, S;Abrányi-Balogh, P;Barti, B;Vámosi, M;Zöldi, M;Barna, L;Urbán, GM;Tóth, AD;Dudok, B;Egyed, A;Deng, H;Leggio, GM;Hunyady, L;van der Stelt, M;Keseru, GM;Katona, I

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NATURE COMMUNICATIONS

2021.

DOI:10.1038/s41467-021-26757-z (Copy DOI)

Semmelweis University authors: Prokop, Susanne Clara, Barti, Benjámin, Zöldi, Miklós, Katona-Urbán, Gabriella, Tóth, András, Dudok, Barna, Hunyady, László,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, School of PhD Studies,

6.

G protein-coupled receptor endocytosis generates spatiotemporal bias in β-arrestin signaling

Tóth, AD;Szalai, B;Kovács, OT;Garger, D;Prokop, S;Soltész-Katona, E;Balla, A;Inoue, A;Várnai, P;Turu, G;Hunyady, L

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SCIENCE SIGNALING

2024.

DOI:10.1126/scisignal.adi0934 (Copy DOI)

Semmelweis University authors: Tóth, András, Szalai, Bence, Kovács, Orsolya Tünde, Prokop, Susanne Clara, Soltész-Katona, Eszter, Balla, András, Várnai, Péter, Turu, Gábor, Hunyady, László,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Belgyógyászati és Hematológiai Klinika,

7.

Role of the Endocannabinoid System in Metabolic Control Processes and in the Pathogenesis of Metabolic Syndrome: An Update

Dörnyei, G;Vass, Z;Juhász, CB;Nádasy, GL;Hunyady, L;Szekeres, M

Q1

BIOMEDICINES

2023.

DOI:10.3390/biomedicines11020306 (Copy DOI)

Semmelweis University authors: Bednárikné Dörnyei, Gabriella, Vass, Zsolt, Nádasy, György László, Hunyady, László, Szekeres, Mária,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Faculty of Health Sciences, Department of Morphology and Physiology,

8.

Functional consequences of spatial, temporal and ligand bias of G protein-coupled receptors

Tóth, AD;Turu, G;Hunyady, L

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NATURE REVIEWS NEPHROLOGY

2024.

DOI:10.1038/s41581-024-00869-3 (Copy DOI)

Semmelweis University authors: Tóth, András, Turu, Gábor, Hunyady, László,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Belgyógyászati és Hematológiai Klinika,

9.

Biased Coupling to β-Arrestin of Two Common Variants of the CB₂ Cannabinoid Receptor

Turu, G;Soltész-Katona, E;Tóth, AD;Juhász, C;Cserzo, M;Misák, A;Balla, A;Caron, MG;Hunyady, L

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FRONTIERS IN ENDOCRINOLOGY

2021.

DOI:10.3389/fendo.2021.714561 (Copy DOI)

Semmelweis University authors: Turu, Gábor, Soltész-Katona, Eszter, Tóth, András, Cserző, Miklós, Misák, Ádám, Balla, András, Hunyady, László,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology,

10.

Functional Rescue of a Nephrogenic Diabetes Insipidus Causing Mutation in the V2 Vasopressin Receptor by Specific Antagonist and Agonist Pharmacochaperones

Szalai, L;Sziraki, A;Erdelyi, LS;Kovacs, KB;Toth, M;Toth, AD;Turu, G;Bonnet, D;Mouillac, B;Hunyady, L;Balla, A

Q1

FRONTIERS IN PHARMACOLOGY

2022.

DOI:10.3389/fphar.2022.811836 (Copy DOI)

Semmelweis University authors: Szalai, Laura, Erdélyi, László Sándor, Kovács, Kinga Bernadett, Tóth, Miklós, Tóth, András, Turu, Gábor, Hunyady, László, Balla, András,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Belgyógyászati és Hematológiai Klinika, Department of Internal Medicine and Oncology,

11.

Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity

Barsi, S;Papp, H;Valdeolivas, A;Tóth, DJ;Kuczmog, A;Madai, M;Hunyady, L;Várnai, P;Saez-Rodriguez, J;Jakab, F;Szalai, B

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PLOS COMPUTATIONAL BIOLOGY

2022.

DOI:10.1371/journal.pcbi.1010021 (Copy DOI)

Semmelweis University authors: Barsi, Szilvia, Tóth, Dániel, Hunyady, László, Várnai, Péter, Szalai, Bence,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology,

12.

A general method for quantifying ligand binding to unmodified receptors using Gaussia luciferase

Tóth, AD;Garger, D;Prokop, S;Soltész-Katona, E;Várnai, P;Balla, A;Turu, G;Hunyady, L

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JOURNAL OF BIOLOGICAL CHEMISTRY

2021.

DOI:10.1016/j.jbc.2021.100366 (Copy DOI)

Semmelweis University authors: Tóth, András, Prokop, Susanne Clara, Soltész-Katona, Eszter, Várnai, Péter, Balla, András, Turu, Gábor, Hunyady, László,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Belgyógyászati és Hematológiai Klinika, School of PhD Studies,

13.

ArreSTick motif controls β-arrestin-binding stability and extends phosphorylation-dependent β-arrestin interactions to non-receptor proteins

Tóth, AD;Soltész-Katona, E;Kis, K;Guti, V;Gilzer, S;Prokop, S;Boros, R;Misák, A;Balla, A;Várnai, P;Turiák, L;Acs, A;Drahos, L;Inoue, A;Hunyady, L;Turu, G

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CELL REPORTS

2024.

DOI:10.1016/j.celrep.2024.114241 (Copy DOI)

Semmelweis University authors: Tóth, András, Soltész-Katona, Eszter, Prokop, Susanne Clara, Misák, Ádám, Balla, András, Várnai, Péter, Turiák, Lilla, Hunyady, László, Turu, Gábor,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Belgyógyászati és Hematológiai Klinika,

14.

V2 vasopressin receptor mutations: future personalized therapy based on individual molecular biology

Erdélyi, LS;Hunyady, L;Balla, A

Q1

FRONTIERS IN ENDOCRINOLOGY

2023.

DOI:10.3389/fendo.2023.1173601 (Copy DOI)

Semmelweis University authors: Erdélyi, László Sándor, Hunyady, László, Balla, András,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Intensive Care Clinic, Department of Anesthesoiology and Intensiv Therapy,

15.

Angiotensin II-Induced Cardiac Effects Are Modulated by Endocannabinoid-Mediated CB₁ Receptor Activation

Miklós, Z;Wafa, D;Nádasy, GL;Tóth, ZE;Besztercei, B;Dörnyei, G;Laska, Z;Benyó, Z;Ivanics, T;Hunyady, L;Szekeres, M

Q1

CELLS

2021.

DOI:10.3390/cells10040724 (Copy DOI)

Semmelweis University authors: Miklós, Zsuzsanna, Wafa, Dina, Nádasy, György László, Tóth, Zsuzsanna, Besztercei, Balázs, Bednárikné Dörnyei, Gabriella, Benyó, Zoltán, Ivanics, Tamás, Hunyady, László, Szekeres, Mária,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Anatómiai, Szövet- és Fejlődéstani Intézet, Department of Physiology, Transzlációs Medicina Intézet, Faculty of Health Sciences, Department of Morphology and Physiology,

16.

Characterization of Type 1 Angiotensin II Receptor Activation Induced Dual-Specificity MAPK Phosphatase Gene Expression Changes in Rat Vascular Smooth Muscle Cells

Gem, JB;Kovacs, KB;Szalai, L;Szakadati, G;Porkolab, E;Szalai, B;Turu, G;Toth, AD;Szekeres, M;Hunyady, L;Balla, A

Q1

CELLS

2021.

DOI:10.3390/cells10123538 (Copy DOI)

Semmelweis University authors: Gém, Janka Borbála, Kovács, Kinga Bernadett, Szalai, Laura, Szakadáti, Gyöngyi, Porkoláb, Edit, Szalai, Bence, Turu, Gábor, Tóth, András, Szekeres, Mária, Hunyady, László, Balla, András,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Belgyógyászati és Hematológiai Klinika, Faculty of Health Sciences, Department of Morphology and Physiology,

17.

An Unexpected Enzyme in Vascular Smooth Muscle Cells: Angiotensin II Upregulates Cholesterol-25-Hydroxylase Gene Expression

Kovács, KB;Szalai, L;Szabó, P;Gém, JB;Barsi, S;Szalai, B;Perey-Simon, B;Turu, G;Tóth, AD;Várnai, P;Hunyady, L;Balla, A

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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2023.

DOI:10.3390/ijms24043968 (Copy DOI)

Semmelweis University authors: Kovács, Kinga Bernadett, Szalai, Laura, Gém, Janka Borbála, Barsi, Szilvia, Szalai, Bence, Turu, Gábor, Tóth, András, Várnai, Péter, Hunyady, László, Balla, András,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Belgyógyászati és Hematológiai Klinika,

18.

Interactions between β-arrestin proteins and the cytoskeletal system, and their relevance to neurodegenerative disorders

Szénási, T;Turu, G;Hunyady, L

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FRONTIERS IN ENDOCRINOLOGY

2023.

DOI:10.3389/fendo.2023.957981 (Copy DOI)

Semmelweis University authors: Turu, Gábor, Hunyady, László,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology,

19.

Cannabinoid receptor type 1 (CB₁R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3

Szanda, G;Jourdan, T;Wisniewski, É;Cinar, R;Godlewski, G;Rajki, A;Liu, J;Chedester, L;Szalai, B;Tóth, AD;Soltész-Katona, E;Hunyady, L;Inoue, A;Horváth, VB;Spät, A;Tam, J;Kunos, G

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ISCIENCE

2023.

DOI:10.1016/j.isci.2023.107207 (Copy DOI)

Semmelweis University authors: Szanda, Gergő, Wisniewski, Éva, Rajki, Anikó, Szalai, Bence, Tóth, András, Soltész-Katona, Eszter, Hunyady, László, Spät, András,

Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Physiology, Belgyógyászati és Hematológiai Klinika,

20.

Proteomic Changes of Osteoclast Differentiation in Rheumatoid and Psoriatic Arthritis Reveal Functional Differences

Kovacs, OT;Toth, E;Ozohanics, O;Soltesz-Katona, E;Marton, N;Buzas, EI;Hunyady, L;Drahos, L;Turu, G;Nagy, G

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FRONTIERS IN IMMUNOLOGY

2022.