Semmelweis Publications
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    • Tóth, Gergő Semmelweis University affiliated publications (2020-2025)

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    Number of publications: 42
    1.
    Cyclodextrin encapsulation enabling the anticancer repositioning of disulfiram: Preparation, analytical and in vitro biological characterization of the inclusion complexes
    Benko, BM;Tóth, G;Moldvai, D;Kádár, S;Szabó, E;Szabó, ZI;Kraszni, M;Szente, L;Fiser, B;Sebestyén, A;Zelkó, R;Sebe, I
    Q1
    INTERNATIONAL JOURNAL OF PHARMACEUTICS
    2024.
    DOI:10.1016/j.ijpharm.2024.124187 (Copy DOI)
    2.
    Simultaneous determination of chiral and achiral impurities of ivabradine on a cellulose tris(3-chloro-4-methylphenylcarbamate) chiral column using polar organic mode
    Ferencz, E;Kovács, B;Boda, F;Foroughbakhshfasaei, M;Kelemen, ÉK;Tóth, G;Szabó, ZI
    Q1
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
    2020.
    DOI:10.1016/j.jpba.2019.112851 (Copy DOI)
    Semmelweis University authors: Tóth, Gergő,
    Semmelweis University departments: Semmelweis University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
    3.
    Arylnaphthalene Lignans with Anti-SARS-CoV-2 and Antiproliferative Activities from the Underground Organs of Linum austriacum and Linum perenne
    Tóth, G;Horváti, K;Kraszni, M;Ausbüttel, T;Pályi, B;Kis, Z;Mucsi, Z;Kovács, GM;Bosze, S;Boldizsár, I
    D1
    JOURNAL OF NATURAL PRODUCTS
    2023.
    DOI:10.1021/acs.jnatprod.2c00580 (Copy DOI)
    4.
    Determination of Chiral Impurity of Naproxen in Different Pharmaceutical Formulations Using Polysaccharide-Based Stationary Phases in Reversed-Phased Mode
    Papp, LA;Krizbai, S;Dobó, M;Hancu, G;Szabó, ZI;Tóth, G
    Q1
    MOLECULES
    2022.
    DOI:10.3390/molecules27092986 (Copy DOI)
    Semmelweis University authors: Dobó, Máté, Tóth, Gergő,
    Semmelweis University departments: Semmelweis University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
    5.
    Enantioseparation and molecular docking study of selected chiral pharmaceuticals on a commercialized phenylcarbamate-β-cyclodextrin column using polar organic mode
    Dobó, M;Adám, M;Fiser, B;Papp, LA;Dombi, G;Sekkoum, K;Szabó, ZI;Tóth, G
    D1
    SCIENTIFIC REPORTS
    2023.
    DOI:10.1038/s41598-023-41941-5 (Copy DOI)
    6.
    Simultaneous Determination of Enantiomeric Purity and Organic Impurities of Dexketoprofen Using Reversed-Phase Liquid Chromatography-Enhancing Enantioselectivity through Hysteretic Behavior and Temperature-Dependent Enantiomer Elution Order Reversal on Po
    Dobó, M;Dombi, G;Köteles, I;Fiser, B;Kis, C;Szabó, ZI;Tóth, G
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2024.
    DOI:10.3390/ijms25052697 (Copy DOI)
    7.
    Enantioselective Binding of Proton Pump Inhibitors to Alpha1-Acid Glycoprotein and Human Serum Albumin-A Chromatographic, Spectroscopic, and In Silico Study
    Dombi, G;Tyukodi, L;Dobó, M;Molnár, G;Rozmer, Z;Szabó, ZI;Fiser, B;Tóth, G
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2024.
    DOI:10.3390/ijms251910575 (Copy DOI)
    8.
    Chiral separation of oxazolidinone analogues by liquid chromatography on polysaccharide stationary phases using polar organic mode
    Dobó, M;Foroughbakhshfasaei, M;Horváth, P;Szabó, ZI;Tóth, G
    Q1
    JOURNAL OF CHROMATOGRAPHY A
    2022.
    DOI:10.1016/j.chroma.2021.462741 (Copy DOI)
    9.
    Comparative Chiral Separation of Thalidomide Class of Drugs Using Polysaccharide-Type Stationary Phases with Emphasis on Elution Order and Hysteresis in Polar Organic Mode
    Foroughbakhshfasaei, M;Dobó, M;Boda, F;Szabó, ZI;Tóth, G
    Q1
    MOLECULES
    2022.
    DOI:10.3390/molecules27010111 (Copy DOI)
    Semmelweis University authors: Dobó, Máté, Tóth, Gergő,
    Semmelweis University departments: Semmelweis University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
    10.
    Enantioselective Human Serum Albumin Binding of Apremilast: Liquid Chromatographic, Fluorescence and Molecular Docking Study
    Dombi, G;Horváth, P;Fiser, B;Mirzahosseini, A;Dobó, M;Szabó, ZI;Tóth, G
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2023.
    DOI:10.3390/ijms24032168 (Copy DOI)
    11.
    Reversed-phase HPLC enantioseparation of pantoprazole using a teicoplanin aglycone stationary phase-Determination of the enantiomer elution order using HPLC-CD analyses
    Papp, LA;Foroughbakhshfasaei, M;Fiser, B;Horváth, P;Kiss, E;Sekkoum, K;Gyéresi, A;Hancu, G;Noszál, B;Szabó, ZI;Tóth, G
    Q3
    CHIRALITY
    2020.
    DOI:10.1002/chir.23146 (Copy DOI)
    12.
    Chiral Recognition Mechanism of Benzyltetrahydroisoquinoline Alkaloids: Cyclodextrin-Mediated Capillary Electrophoresis, Chiral HPLC, and NMR Spectroscopy Study
    Várnagy, E;Tóth, G;Hosztafi, S;Dobó, M;Fejos, I;Béni, S
    Q1
    MOLECULES
    2025.
    DOI:10.3390/molecules30051125 (Copy DOI)
    13.
    The Use of Dual Cyclodextrin Chiral Selector Systems in the Enantioseparation of Pharmaceuticals by Capillary Electrophoresis: An Overview
    Hancu, G;Papp, LA;Tóth, G;Kelemen, H
    Q1
    MOLECULES
    2021.
    DOI:10.3390/molecules26082261 (Copy DOI)
    Semmelweis University authors: Tóth, Gergő,
    Semmelweis University departments: Semmelweis University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
    14.
    Inclusion complexation of the anticancer drug pomalidomide with cyclodextrins: fast dissolution and improved solubility
    Szabó, ZI;Orbán, G;Borbás, E;Csicsák, D;Kádár, S;Fiser, B;Dobó, M;Horváth, P;Kiss, E;Budai, L;Dobos, J;Pálla, T;Orfi, L;Völgyi, G;Toth, G
    Q1
    HELIYON
    2021.
    DOI:10.1016/j.heliyon.2021.e07581 (Copy DOI)
    15.
    Liquid chromatographic method for the simultaneous determination of achiral and chiral impurities of dapoxetine in approved and counterfeit products
    Tóth, G;Fogarasi, E;Bartalis-Fábián, A;Foroughbakhshfasaei, M;Boldizsár, I;Darcsi, A;Lohner, S;Scriba, GKE;Szabó, ZI
    Q1
    JOURNAL OF CHROMATOGRAPHY A
    2020.
    DOI:10.1016/j.chroma.2020.461388 (Copy DOI)
    16.
    Enantioseparation of Mirabegron Using Cyclodextrin-based Chiral Columns: High-performance Liquid Chromatography and Molecular Modeling Study
    Mhammad, A;Dombi, G;Dobó, M;Szabó, ZI;Fiser, B;Tóth, G
    Q2
    JOURNAL OF SEPARATION SCIENCE
    2025.
    DOI:10.1002/jssc.70132 (Copy DOI)
    17.
    Chiral Separation of Vildagliptin by Capillary Electrophoresis-The Study of Enantiomeric Complexation
    Papp, LA;Hancu, G;Szabó, ZI;Székely-Szentmiklósi, B;Gáti, T;Fiser, B;Kraszni, M;Tóth, G
    Q2
    SYMMETRY-BASEL
    2024.
    DOI:10.3390/sym16010017 (Copy DOI)
    18.
    Determination of the Enantiomeric Purity of Solriamfetol by High-Performance Liquid Chromatography in Polar Organic Mode Using Polysaccharide-Type Chiral Stationary Phases
    Koteles, I;Foroughbakhshfasaei, M;Dobo, M;adam, M;Boldizsar, I;Szabo, ZI;Toth, G
    Q3
    CHROMATOGRAPHIA
    2020.
    DOI:10.1007/s10337-020-03911-1 (Copy DOI)
    19.
    Bioequivalence prediction with small-scale biphasic dissolution and simultaneous dissolution-permeation apparatus - An aripiprazole case study
    Kádár, S;Kennedy, A;Lee, S;Ruiz, R;Farkas, A;Tozsér, P;Csicsák, D;Tóth, G;Sinkó, B;Borbás, E
    Q1
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
    2024.
    DOI:10.1016/j.ejps.2024.106782 (Copy DOI)
    20.
    Chiral Separation of Apremilast by Capillary Electrophoresis Using Succinyl-β-Cyclodextrin-Reversal of Enantiomer Elution Order by Cationic Capillary Coating
    Szabó, ZI;Benko, BM;Bartalis-Fábián, A;Iványi, R;Varga, E;Szocs, L;Tóth, G
    Q1
    MOLECULES
    2023.
    DOI:10.3390/molecules28083310 (Copy DOI)
    21.
    Understanding the pH Dependence of Supersaturation State-A Case Study of Telmisartan
    Kádár, S;Csicsák, D;Tozsér, P;Farkas, A;Pálla, T;Mirzahosseini, A;Tóth, B;Tóth, G;Fiser, B;Horváth, P;Madarász, J;Avdeef, A;Takács-Novák, K;Sinkó, B;Borbás, E;Völgyi, G
    Q1
    PHARMACEUTICS
    2022.
    DOI:10.3390/pharmaceutics14081635 (Copy DOI)
    22.
    The grass root endophytic fungus Flavomyces fulophazii: An abundant source of tetramic acid and chlorinated azaphilone derivatives
    Berek-Nagy, PJ;Tóth, G;Bosze, S;Horváth, LB;Darcsi, A;Csíkos, S;Knapp, DG;Kovács, GM;Boldizsár, I
    Q1
    PHYTOCHEMISTRY
    2021.
    DOI:10.1016/j.phytochem.2021.112851 (Copy DOI)
    23.
    Enantioseparation of solriamfetol and its major impurity phenylalaninol by capillary electrophoresis using sulfated gamma cyclodextrin
    Fejos, I;Tóth, G;Várnai, B;Szabó, ZI;Köteles, I;Malanga, M;Béni, S
    Q2
    ELECTROPHORESIS
    2021.
    DOI:10.1002/elps.202100076 (Copy DOI)
    24.
    Simultaneous Determination of Escitalopram Impurities including the R-enantiomer on a Cellulose tris(3,5-Dimethylphenylcarbamate)-Based Chiral Column in Reversed-Phase Mode
    Szabó, ZI;Bartalis-Fábián, A;Tóth, G
    Q1
    MOLECULES
    2022.
    DOI:10.3390/molecules27249022 (Copy DOI)
    Semmelweis University authors: Tóth, Gergő,
    Semmelweis University departments: Semmelweis University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
    25.
    Synthesis of Potential Haptens with Morphine Skeleton and Determination of Protonation Constants
    Köteles, I;Mazák, K;Tóth, G;Tuz, B;Hosztafi, S
    Q1
    MOLECULES
    2020.
    DOI:10.3390/molecules25174009 (Copy DOI)
    26.
    Untargeted metabolomic analyses support the main phylogenetic groups of the common plant-associated Alternaria fungi isolated from grapevine (Vitis vinifera)
    Molnár, A;Knapp, DG;Lovas, M;Tóth, G;Boldizsár, I;Váczy, KZ;Kovács, GM
    D1
    SCIENTIFIC REPORTS
    2023.
    DOI:10.1038/s41598-023-46020-3 (Copy DOI)
    27.
    Tissue-Specific Accumulation and Isomerization of Valuable Phenylethanoid Glycosides from Plantago and Forsythia Plants
    Zürn, M;Tóth, G;Ausbüttel, T;Mucsi, Z;Horváti, K;Bosze, S;Sütöri-Diószegi, M;Pályi, B;Kis, Z;Noszál, B;Boldizsár, I
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2021.
    DOI:10.3390/ijms22083880 (Copy DOI)
    28.
    The Applicability of Chromatographic Retention Modeling on Chiral Stationary Phases in Reverse-Phase Mode: A Case Study for Ezetimibe and Its Impurities
    Ferencz, E;Kelemen, EK;Obreja, M;Toth, G;Urkon, M;Zoeldhegyi, A;Sipos, E;Szabo, ZI
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2023.
    DOI:10.3390/ijms242216097 (Copy DOI)
    Semmelweis University authors: Tóth, Gergő,
    Semmelweis University departments: Semmelweis University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
    29.
    Synthesis of 3-O-Carboxyalkyl Morphine Derivatives and Characterization of Their Acid-Base Properties
    Köteles, I;Mazák, K;Tóth, G;Horváth, P;Kiss, E;Tuz, B;Hosztafi, S
    Q2
    CHEMISTRY & BIODIVERSITY
    2021.
    DOI:10.1002/cbdv.202100135 (Copy DOI)
    30.
    Analytical quality by design-compliant retention modeling for exploring column interchangeabilities in separating ezetimibe and its related substances
    Ferencz, E;Zöldhegyi, A;Kelemen, ÉK;Obreja, M;Urkon, M;Sipos, E;Tóth, G;Molnár, I;Szabó, ZI
    Q1
    JOURNAL OF CHROMATOGRAPHY A
    2022.
    DOI:10.1016/j.chroma.2022.463494 (Copy DOI)
    Semmelweis University authors: Tóth, Gergő,
    Semmelweis University departments: Semmelweis University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
    31.
    Chiral separation in the class of proton pump inhibitors by chromatographic and electromigration techniques: An overview
    Papp, LA;Hancu, G;Kelemen, H;Tóth, G
    Q2
    ELECTROPHORESIS
    2021.
    DOI:10.1002/elps.202100032 (Copy DOI)
    Semmelweis University authors: Tóth, Gergő,
    Semmelweis University departments: Semmelweis University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
    32.
    Possibilities and limitations of computer assisted chiral HPLC method development for ozanimod on polysaccharide based chiral stationary phases
    Ferencz, E;Szabó, ZI;Zöldhegyi, A;Dombi, G;Molnár, G;Dobo, M;Varga, E;Molnár, I;Tóth, G
    Q1
    SCIENTIFIC REPORTS
    2024.
    DOI:10.1038/s41598-024-78415-1 (Copy DOI)
    33.
    Bicarbonate Evokes Reciprocal Changes in Intracellular Cyclic di-GMP and Cyclic AMP Levels in Pseudomonas aeruginosa
    Ruksakiet, K;Stercz, B;Tóth, G;Jaikumpun, P;Gróf, I;Tengölics, R;Lohinai, ZM;Horváth, P;Deli, MA;Steward, MC;Dobay, O;Zsembery, A
    Q1
    BIOLOGY-BASEL
    2021.
    DOI:10.3390/biology10060519 (Copy DOI)
    34.
    Enantioseparation of Proton Pump Inhibitors by HPLC on Polysaccharide-Type Stationary Phases: Enantiomer Elution Order Reversal, Thermodynamic Characterization, and Hysteretic Effect
    Dobó, M;Molnár, G;Mhammad, A;Dombi, G;Mirzahosseini, A;Szabó, ZI;Tóth, G
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2025.
    DOI:10.3390/ijms26157217 (Copy DOI)
    35.
    Gradient, reversed-phase HPLC method for simultaneous determination of chemical and enantiomeric impurities of dexibuprofen in a single run
    Mhammad, A;Dombi, G;Dobó, M;Simon, B;Szabó, ZI;Tóth, G
    Q1
    JOURNAL OF CHROMATOGRAPHY A
    2025.
    DOI:10.1016/j.chroma.2025.466210 (Copy DOI)
    36.
    Comparison of lipophilic and size-exclusion membranes: the effect of stirring and cyclodextrin in the donor compartment
    Tozsér, P;Kádár, S;Szabó, E;Dobó, M;Tóth, G;Balogh, GT;Sóti, P;Sinkó, B;Borbás, E
    Q1
    ADMET AND DMPK
    2025.
    DOI:10.5599/admet.2753 (Copy DOI)
    37.
    Development of Low-Dose Disulfiram Rectal Suppository Intended for Application in Post-Treatment Lyme Disease Syndrome
    Benko, BM;Szabo, BI;Kadar, S;Szabo, E;Toth, G;Szente, L;Tonka-Nagy, P;Zelko, R;Sebe, I
    D1
    PHARMACEUTICS
    2025.
    DOI:10.3390/pharmaceutics17070849 (Copy DOI)
    38.
    Malonyl-Caffeoylquinic Acids and Malonyl-Flavonoid-Glucosides from Three Edible Apiaceae Plants Anthriscus Cerefolium, Anthriscus Sylvestris, and Chaerophyllum Bulbosum
    Nazli, A;Gaborova, M;Ausbuttel, T;Stipsicz, B;Toth, G;Bösze, S;Beni, S;Boldizsar, I
    Q1
    ACS OMEGA
    2025.
    DOI:10.1021/acsomega.5c03770 (Copy DOI)
    39.
    Machine learning-assisted retention time predictions on a cellulose Tris (3,5)-dimethylphenylcarbamate column in polar organic mode
    Imre, A;Dombi, G;Dobó, M;Mhammad, A;Ferencz, E;Balogh, B;Vincze, A;Szabó, ZI;Balogh, GT;Rácz, A;Tóth, G
    Q1
    ANALYTICA CHIMICA ACTA
    2025.
    DOI:10.1016/j.aca.2025.344733 (Copy DOI)
    40.
    Chiral Separation of Oxazolidinone Analogs by Capillary Electrophoresis Using Anionic Cyclodextrins as Chiral Selectors: Emphasis on Enantiomer Migration Order
    Szabó, ZI;Boda, F;Fiser, B;Dobó, M;Szos, L;Tóth, G
    Q1
    MOLECULES
    2023.
    DOI:10.3390/molecules28114530 (Copy DOI)
    Semmelweis University authors: Dobó, Máté, Tóth, Gergő,
    Semmelweis University departments: Semmelweis University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry,
    41.
    Enantioselective Complexation of Xylopinine: A Cyclodextrin-Assisted CE and NMR Study
    Várnagy, E;Tóth, G;Hosztafi, S;Malanga, M;Fejos, I;Béni, S
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2025.
    DOI:10.3390/ijms26199405 (Copy DOI)
    42.
    Physicochemical Characterization, Cyclodextrin Complexation, and Protonation State-Dependent Receptor Binding of Selected Tyrosine Kinase Inhibitors
    Jánoska, Ádám; Szabó, Zoltán-István; Szőcs, Levente; Fiser, Béla; Tóth, Gergő;
    Q2
    JOURNAL OF MOLECULAR STRUCTURE 0022-2860 1872-8014
    2025.
    DOI:10.1016/j.molstruc.2025.144518 (Copy DOI)

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