Semmelweis Publications
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    • Sinkovits, György Semmelweis University affiliated publications (2020-2025)

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    Number of publications: 24
    1.
    Caplacizumab use in immune-mediated thrombotic thrombocytopenic purpura: an international multicentre retrospective Cohort study (The Capla 1000+project)
    Coppo, P;Bubenheim, M;Benhamou, Y;Voelker, L;Brinkkoetter, P;Kuehne, L;Knoebl, P;Mingot-Castellano, ME;Pascual-Izquierdo, C;de la Rubia, J;Garma, JD;Chaturvedi, S;Masias, C;Mazepa, M;Zheng, XL;Sinkovits, G;Reti, M;Patriquin, CJ;Pavenski, K;Boechat, T;Farias, J;Ribeiro, EFO;Andrade, MLLD;Veyradier, A;Joly, B;Bouzid, R;Sakai, K;Matsumoto, M;Agosti, P;Mancini, I;Peyvandi, F;Gavriilaki, E;Stubbs, M;Hmaid, A;Cataland, S;Laemmle, B;Scully, M
    D1
    ECLINICALMEDICINE
    2025.
    DOI:10.1016/j.eclinm.2025.103168 (Copy DOI)
    Semmelweis University authors: Sinkovits, György,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Belgyógyászati és Hematológiai Klinika,
    2.
    Complement Overactivation and Consumption Predicts In-Hospital Mortality in SARS-CoV-2 Infection
    Sinkovits, G;Mezo, B;Réti, M;Müller, V;Iványi, Z;Gál, J;Gopcsa, L;Reményi, P;Szathmáry, B;Lakatos, B;Szlávik, J;Bobek, I;Prohászka, ZZ;Förhécz, Z;Csuka, D;Hurler, L;Kajdácsi, E;Cervenak, L;Kiszel, P;Masszi, T;Valyi-Nagy, I;Prohászka, Z
    Q1
    FRONTIERS IN IMMUNOLOGY
    2021.
    DOI:10.3389/fimmu.2021.663187 (Copy DOI)
    3.
    Class switch towards spike protein-specific IgG4 antibodies after SARS-CoV-2 mRNA vaccination depends on prior infection history
    Kiszel, P;Sík, P;Miklós, J;Kajdácsi, E;Sinkovits, G;Cervenak, L;Prohászka, Z
    D1
    SCIENTIFIC REPORTS
    2023.
    DOI:10.1038/s41598-023-40103-x (Copy DOI)
    4.
    Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura
    Roose, E;Tellier, AS;Tellier, E;Sinkovits, G;Joly, BS;Dekimpe, C;Kaplanski, G;Le Besnerais, M;Mancini, I;Falter, T;Von Auer, C;Feys, HB;Reti, M;Rossmann, H;Vandenbulcke, A;Pareyn, I;Voorberg, J;Greinacher, A;Benhamou, Y;Deckmyn, H;Fijnheer, R;Prohaszka, Z;Peyvandi, F;Lämmle, B;Coppo, P;De Meyer, SF;Veyradier, A;Vanhoorelbeke, K
    D1
    BLOOD
    2020.
    DOI:10.1182/blood.2019004221 (Copy DOI)
    5.
    Annual incidence and severity of acute episodes in hereditary thrombotic thrombocytopenic purpura
    Tarasco, E;Bütikofer, L;Friedman, KD;George, JN;Hrachovinova, I;Knöbl, PN;Matsumoto, M;von Krogh, AS;Aebi-Huber, I;Cermakova, Z;Górska-Kosicka, M;Jalowiec, KA;Largiadèr, CR;Prohászka, Z;Sinkovits, G;Windyga, J;Lämmle, B;Hovinga, JAK
    D1
    BLOOD
    2021.
    DOI:10.1182/blood.2020009801 (Copy DOI)
    6.
    Hemolytic uremic syndrome in the setting of COVID-19 successfully treated with complement inhibition therapy: An instructive case report of a previously healthy toddler and review of literature
    Matosevic, M;Kos, I;Davidovic, M;Ban, MJ;Matkovic, H;Jakopcic, I;Brinar, IV;Szilagyi, A;Csuka, D;Sinkovits, G;Prohaszka, Z;Vrljicak, K;Lamot, L
    Q2
    FRONTIERS IN PEDIATRICS
    2023.
    DOI:10.3389/fped.2023.1092860 (Copy DOI)
    7.
    Decreased circulating dipeptidyl peptidase-4 enzyme activity is prognostic for severe outcomes in COVID-19 inpatients
    Nádasdi, A;Sinkovits, G;Bobek, I;Lakatos, B;Förhécz, Z;Prohászka, ZZ;Réti, M;Arató, M;Cseh, G;Masszi, T;Merkely, B;Ferdinandy, P;Vályi-Nagy, I;Prohászka, Z;Firneisz, G
    Q3
    BIOMARKERS IN MEDICINE
    2022.
    DOI:10.2217/bmm-2021-0717 (Copy DOI)
    8.
    Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups
    Hurler, L;Szilágyi, A;Mescia, F;Bergamaschi, L;Mezo, B;Sinkovits, G;Réti, M;Müller, V;Iványi, Z;Gál, J;Gopcsa, L;Reményi, P;Szathmáry, B;Lakatos, B;Szlávik, J;Bobek, I;Prohászka, ZZ;Förhécz, Z;Csuka, D;Kajdácsi, E;Cervenak, L;Kiszel, P;Masszi, T;Vályi-Nagy, I;Wüerzner, R;Lyons, PA;Toonen, EJM;Prohászka, Z
    Q1
    FRONTIERS IN IMMUNOLOGY
    2023.
    DOI:10.3389/fimmu.2023.1162171 (Copy DOI)
    9.
    Associations between the von Willebrand Factor-ADAMTS13 Axis, Complement Activation, and COVID-19 Severity and Mortality
    Sinkovits, G;Réti, M;Müller, V;Iványi, Z;Gál, J;Gopcsa, L;Reményi, P;Szathmáry, B;Lakatos, B;Szlávik, J;Bobek, I;Prohászka, ZZ;Förhecz, Z;Mezo, B;Csuka, D;Hurler, L;Kajdácsi, E;Cervenak, L;Kiszel, P;Masszi, T;Vályi-Nagy, I;Prohászka, Z
    Q1
    THROMBOSIS AND HAEMOSTASIS
    2022.
    DOI:10.1055/s-0041-1740182 (Copy DOI)
    10.
    Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs
    Hurler, L;Toonen, EJM;Kajdácsi, E;van Bree, B;Brandwijk, RJMGE;de Bruin, W;Lyons, PA;Bergamaschi, L;Sinkovits, G;Cervenak, L;Würzner, R;Prohászka, Z
    Q1
    FRONTIERS IN IMMUNOLOGY
    2022.
    DOI:10.3389/fimmu.2022.1039765 (Copy DOI)
    11.
    Open ADAMTS-13 conformation index predicts earlier relapse in immune-mediated thrombotic thrombocytopenic purpura
    De Waele, L;Sakai, K;Mancini, I;Sinkovits, G;Falter, T;Inoue, T;Agosti, P;Rossmann, H;Von Auer, C;Tersteeg, C;Meyer, SFD;Joly, BS;Veyradier, A;Coppo, P;Fijnheer, R;Peyvandi, F;Prohászka, Z;Laemmle, B;Vanhoorelbeke, K
    D1
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS
    2024.
    DOI:10.1016/j.jtha.2023.10.014 (Copy DOI)
    12.
    Complement Levels at Admission Reflecting Progression to Severe Acute Kidney Injury (AKI) in Coronavirus Disease 2019 (COVID-19): A Multicenter Prospective Cohort Study
    Henry, BM;Sinkovits, G;Szergyuk, I;de Oliveira, MHS;Lippi, G;Benoit, JL;Favaloro, EJ;Pode-Shakked, N;Benoit, SW;Cooper, DS;Muller, V;Ivanyi, Z;Gal, J;Reti, M;Gopcsa, L;Remenyi, P;Szathmary, B;Lakatos, B;Szlavik, J;Bobek, I;Prohaszka, ZZ;Forhecz, Z;Csuka, D;Hurler, L;Kajdacsi, E;Cervenak, L;Mezo, B;Kiszel, P;Masszi, T;Valyi-Nagy, I;Prohaszka, Z
    Q1
    FRONTIERS IN MEDICINE
    2022.
    DOI:10.3389/fmed.2022.796109 (Copy DOI)
    13.
    Immunogenic hotspots in the spacer domain of ADAMTS13 in immune-mediated thrombotic thrombocytopenic purpura
    Pereira, LCV;Roose, E;Graça, NAG;Sinkovits, G;Kangro, K;Joly, BS;Tellier, E;Kaplanski, G;Falter, T;Von Auer, C;Rossmann, H;Feys, HB;Reti, M;Prohaszka, Z;Lämmle, B;Voorberg, J;Coppo, P;Veyradier, A;De Meyer, SF;Männik, A;Vanhoorelbeke, K
    D1
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS
    2021.
    DOI:10.1111/jth.15170 (Copy DOI)
    14.
    Prognostic Value of Baseline Serum Pro-Inflammatory Cytokines in Severe Multisystem Inflammatory Syndrome in Children
    Bartha-Tatár, A;Sinkovits, G;Schnur, J;Maráczi, V;Dávid, M;Zsigmond, B;Rimanóczy, E;Szalay, B;Biró, E;Beko, G;Varga, P;Szabo, T;Fagyas, M;Fejes, Z;Kappelmayer, J;Nagy, B Jr
    Q1
    JOURNAL OF CLINICAL MEDICINE
    2024.
    DOI:10.3390/jcm13237177 (Copy DOI)
    Semmelweis University authors: Sinkovits, György,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Belgyógyászati és Hematológiai Klinika,
    15.
    Validation of Early Increase in Complement Activation Marker sC5b-9 as a Predictive Biomarker for the Development of Thrombotic Microangiopathy After Stem Cell Transplantation
    Mezö, B;Horvath, O;Sinkovits, G;Veszeli, N;Krivan, G;Prohaszka, Z
    Q1
    FRONTIERS IN MEDICINE
    2020.
    DOI:10.3389/fmed.2020.569291 (Copy DOI)
    16.
    Anti-ADAMTS13 autoantibody profiling in patients with immune-mediated thrombotic thrombocytopenic purpura
    Kangro, K;Roose, E;Joly, BS;Sinkovits, G;Falter, T;von Auer, C;Rossmann, H;Reti, M;Voorberg, J;Prohászka, Z;Lämmle, B;Coppo, P;Veyradier, A;De Meyer, SF;Männik, A;Vanhoorelbeke, K
    D1
    BLOOD ADVANCES
    2021.
    DOI:10.1182/bloodadvances.2020004172 (Copy DOI)
    17.
    Evidence, detailed characterization and clinical context of complement activation in acute multisystem inflammatory syndrome in children
    Sinkovits, G;Schnur, J;Hurler, L;Kiszel, P;Prohászka, ZZ;Sík, P;Kajdácsi, E;Cervenak, L;Maráczi, V;Dávid, M;Zsigmond, B;Rimanóczy, E;Bereczki, C;Willems, L;Toonen, EJM;Prohászka, Z
    D1
    SCIENTIFIC REPORTS
    2022.
    DOI:10.1038/s41598-022-23806-5 (Copy DOI)
    18.
    sMR and PTX3 levels associate with COVID-19 outcome and survival but not with Long COVID
    Hurler, L;Mescia, F;Bergamaschi, L;Kajdácsi, E;Sinkovits, G;Cervenak, L;Prohászka, Z;Lyons, PA;Toonen, EJM
    D1
    ISCIENCE
    2024.
    DOI:10.1016/j.isci.2024.110162 (Copy DOI)
    19.
    Circulating mortalin in blood and activation of the alternative complement pathway as risk indicators in COVID-19 infection
    Avraham, M;Sinkovits, G;Hurler, L;Prohászka, Z;Fishelson, Z
    Q1
    FRONTIERS IN IMMUNOLOGY
    2024.
    DOI:10.3389/fimmu.2024.1337215 (Copy DOI)
    20.
    Anti-Inflammatory Cytokine Profiles in Thrombotic Thrombocytopenic Purpura-Differences Compared to COVID-19
    Demeter, F;Bihari, G;Vadicsku, D;Sinkovits, G;Kajdácsi, E;Horváth, L;Réti, M;Müller, V;Iványi, Z;Gál, J;Gopcsa, L;Reményi, P;Szathmáry, B;Lakatos, B;Szlávik, J;Bobek, I;Prohászka, ZZ;Förhécz, Z;Masszi, T;Vályi-Nagy, I;Prohászka, Z;Cervenak, L
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2024.
    DOI:10.3390/ijms251810007 (Copy DOI)
    21.
    High anti-ADAMTS13 IgG Levels after Plasma Exchange Predict Delayed ADAMTS13 Normalization in Immune-mediated Thrombotic Thrombocytopenic Purpura
    Réti, M;Icleanu, AA;Várkonyi, A;Király, A;Bogsch, L;Farkas, Z;Reményi, P;Prohászka, Z;Sinkovits, G
    Q1
    THROMBOSIS AND HAEMOSTASIS
    2025.
    DOI:10.1055/a-2685-8118 (Copy DOI)
    22.
    Delayed Onset of Thrombotic Microangiopathy (TMA) upon Prolonged Carfilzomib Therapy in Multiple Myeloma: A Case Report and Comprehensive Review
    Ceglédi, A;Király, A;Várkonyi, A;Tasnády, S;Andrikovics, H;Fekete, M;Szabó, BG;Szemlaky, Z;Szilágyi, A;Sinkovits, G;Prohászka, Z;Réti, M;Mikala, G
    Q1
    PHARMACEUTICALS
    2024.
    DOI:10.3390/ph17121722 (Copy DOI)
    23.
    Von Willebrand Factor and Platelet Levels before Conditioning Chemotherapy Indicate Bone Marrow Regeneration following Autologous Hematopoietic Stem Cell Transplantation
    Radnay, Z;Illés, A;Udvardy, M;Prohászka, Z;Sinkovits, G;Csányi, MC;Kellermayer, M;Kiss, A;Hársfalvi, J
    D1
    TRANSPLANTATION AND CELLULAR THERAPY
    2022.
    DOI:10.1016/j.jtct.2022.08.028 (Copy DOI)
    24.
    In vitro complement activation via nucleocapsid and spike proteins of SARS-CoV-2 in COVID-19 patients
    Kiszel, Petra; Miklós, János; Kajdácsi, Erika; Sinkovits, György; Cervenak, László; Prohászka, Zoltán;
    Q1
    SCIENTIFIC REPORTS 2045-2322
    2025.
    DOI:10.1038/s41598-025-20926-6 (Copy DOI)

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