Semmelweis Publications
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    • Sayour, Alex Ali Semmelweis University affiliated publications (2021-2026)

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    Number of publications: 41
    1.
    AIM2-driven inflammasome activation in heart failure
    Onódi, Z;Ruppert, M;Kucsera, D;Sayour, AA;Tóth, VE;Koncsos, G;Novák, J;Brenner, GB;Makkos, A;Baranyai, T;Giricz, Z;Görbe, A;Leszek, P;Gyöngyösi, M;Horváth, IG;Schulz, R;Merkely, B;Ferdinandy, P;Radovits, T;Varga, ZV
    D1
    CARDIOVASCULAR RESEARCH
    2021.
    DOI:10.1093/cvr/cvab202 (Copy DOI)
    2.
    Association of Right Ventricular Functional Parameters With Adverse Cardiopulmonary Outcomes: A Meta-analysis
    Sayour, AA;Tokodi, M;Celeng, C;Takx, RAP;Fabian, A;Lakatos, BK;Friebel, R;Surkova, E;Merkely, B;Kovacs, A
    D1
    JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
    2023.
    DOI:10.1016/j.echo.2023.01.018 (Copy DOI)
    3.
    Truncated titin is structurally integrated into the human dilated cardiomyopathic sarcomere
    Kellermayer, D;Tordai, H;Kiss, B;Török, G;Péter, DM;Sayour, AA;Pólos, M;Hartyánszky, I;Szilveszter, B;Labeit, S;Gángó, A;Bedics, G;Bödör, C;Radovits, T;Merkely, B;Kellermayer, MSZ
    D1
    JOURNAL OF CLINICAL INVESTIGATION
    2024.
    DOI:10.1172/JCI169753 (Copy DOI)
    4.
    Novel insights into the athlete's heart: is myocardial work the new champion of systolic function?
    Tokodi, M;Oláh, A;Fábián, A;Lakatos, BK;Hizoh, I;Ruppert, M;Sayour, AA;Barta, BA;Kiss, O;Sydó, N;Csulak, E;Ladányi, Z;Merkely, B;Kovács, A;Radovits, T
    D1
    EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
    2022.
    DOI:10.1093/ehjci/jeab162 (Copy DOI)
    5.
    The anti-fibrotic effects of novel heart failure pharmacotherapies in advanced heart failure patients
    Nagy, D;Radovits, T;Bálint, T;Horváth, Z;Kocsis-Balogh, P;Toth, AG;Oláh, A;Sayour, AA;Barta, BA;Merkely, B;Ruppert, M
    D1
    BRITISH JOURNAL OF PHARMACOLOGY
    2026.
    DOI:10.1111/bph.70250 (Copy DOI)
    6.
    Myocardial work index: a marker of left ventricular contractility in pressure-induced or volume overload-induced heart failure
    Lakatos, BK;Ruppert, M;Tokodi, M;Oláh, A;Braun, S;Karime, C;Ladányi, Z;Sayour, AA;Barta, BA;Merkely, B;Radovits, T;Kovács, A
    Q2
    ESC HEART FAILURE
    2021.
    DOI:10.1002/ehf2.13314 (Copy DOI)
    7.
    Effect of pharmacological selectivity of SGLT2 inhibitors on cardiovascular outcomes in patients with type 2 diabetes: a meta-analysis
    Sayour, AA;Oláh, A;Ruppert, M;Barta, BA;Merkely, B;Radovits, T
    Q1
    SCIENTIFIC REPORTS
    2024.
    DOI:10.1038/s41598-024-52331-w (Copy DOI)
    8.
    Sodium-glucose cotransporter 2 inhibitors reduce myocardial infarct size in preclinical animal models of myocardial ischaemia-reperfusion injury: a meta-analysis
    Sayour, AA;Celeng, C;Oláh, A;Ruppert, M;Merkely, B;Radovits, T
    D1
    DIABETOLOGIA
    2021.
    DOI:10.1007/s00125-020-05359-2 (Copy DOI)
    9.
    Inflammasome activation in end-stage heart failure-associated atrial fibrillation
    Kugler, S;Onódi, Z;Ruppert, M;Sayour, AA;Oláh, A;Benke, K;Ferdinandy, P;Merkely, B;Radovits, T;Varga, ZV
    Q1
    ESC HEART FAILURE
    2022.
    DOI:10.1002/ehf2.13972 (Copy DOI)
    10.
    The Sodium-Glucose Cotransporter-2 Inhibitor Canagliflozin Alleviates Endothelial Dysfunction Following In Vitro Vascular Ischemia/Reperfusion Injury in Rats
    Korkmaz-Icöz, S;Kocer, C;Sayour, AA;Kraft, P;Benker, M;Abulizi, S;Georgevici, AI;Brlecic, P;Radovits, T;Loganathan, S;Karck, M;Szabó, G
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2021.
    DOI:10.3390/ijms22157774 (Copy DOI)
    11.
    Mesenchymal stem cell-derived conditioned medium protects vascular grafts of brain-dead rats against in vitro ischemia/reperfusion injury
    Korkmaz-Icöz, S;Zhou, PY;Guo, YX;Loganathan, S;Brlecic, P;Radovits, T;Sayour, AA;Ruppert, M;Veres, G;Karck, M;Szabó, G
    Q1
    STEM CELL RESEARCH & THERAPY
    2021.
    DOI:10.1186/s13287-021-02166-3 (Copy DOI)
    12.
    Alpha-1-Antitrypsin Protects Vascular Grafts of Brain-Dead Rats Against Ischemia/Reperfusion Injury
    Ding, QW;Loganathan, S;Zhou, PY;Sayour, AA;Brlecic, P;Radovits, T;Domain, R;Korkmaz, B;Karck, M;Szabó, G;Korkmaz-Icöz, S
    Q1
    JOURNAL OF SURGICAL RESEARCH
    2023.
    DOI:10.1016/j.jss.2022.11.047 (Copy DOI)
    13.
    Sex similarities and differences in the reverse and anti-remodeling effect of pressure unloading therapy in a rat model of aortic banding and debanding
    Ruppert, M;Barta, BA;Korkmaz-Icöz, S;Loganathan, S;Oláh, A;Sayour, AA;Benke, K;Nagy, D;Bálint, T;Karck, M;Schilling, O;Merkely, B;Radovits, T;Szabó, G
    Q1
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    2022.
    DOI:10.1152/ajpheart.00654.2021 (Copy DOI)
    14.
    Multiorgan characterization of inflammasome component expression in a rat model of advanced heart failure
    Nagy, D;Onodi, Z;Kocsis, M;Tóth, A;Bálint, T;Oláh, A;Sayour, AA;Barta, BA;Merkely, B;Ferdinandy, P;Radovits, T;Varga, ZV;Ruppert, M
    Q2
    ESC HEART FAILURE
    2025.
    DOI:10.1002/ehf2.15362 (Copy DOI)
    15.
    Graft Preservation Solution DuraGraft(R) Alleviates Vascular Dysfunction Following In Vitro Ischemia/Reperfusion Injury in Rats
    Korkmaz-Icöz, S;Ballikaya, B;Soethoff, J;Kraft, P;Sayour, AA;Radovits, T;Loganathan, S;Karck, M;Szabó, G;Veres, G
    Q1
    PHARMACEUTICALS
    2021.
    DOI:10.3390/ph14101028 (Copy DOI)
    16.
    Balanced Intense Exercise Training Induces Atrial Oxidative Stress Counterbalanced by the Antioxidant System and Atrial Hypertrophy That Is Not Associated with Pathological Remodeling or Arrhythmogenicity
    Oláh, A;Barta, BA;Sayour, AA;Ruppert, M;Virág-Tulassay, E;Novák, J;Varga, ZV;Ferdinandy, P;Merkely, B;Radovits, T
    Q1
    ANTIOXIDANTS
    2021.
    DOI:10.3390/antiox10030452 (Copy DOI)
    17.
    Pharmacological inhibition of the cysteine protease cathepsin C improves graft function after heart transplantation in rats
    Liu, BE;Korkmaz, B;Kraft, P;Mayer, T;Sayour, AA;Grundl, MA;Domain, R;Karck, M;Szabó, G;Korkmaz-Icöz, S
    D1
    JOURNAL OF TRANSLATIONAL MEDICINE
    2023.
    DOI:10.1186/s12967-023-04659-6 (Copy DOI)
    Semmelweis University authors: Sayour, Alex Ali,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Cardiovascular Center,
    18.
    Impact of cardiovascular magnetic resonance-derived right ventricular ejection fraction on adverse outcomes: A robust Bayesian model-averaged meta-analysis
    Kitano, T;Bartos, F;Nabeshima, Y;Sayour, AA;Kovács, A;Takeuchi, M
    D1
    JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
    2024.
    DOI:10.1016/j.jocmr.2024.101118 (Copy DOI)
    19.
    Left Ventricular SGLT1 Protein Expression Correlates with the Extent of Myocardial Nitro-Oxidative Stress in Rats with Pressure and Volume Overload-Induced Heart Failure
    Sayour, AA;Ruppert, M;Oláh, A;Benke, K;Barta, BA;Zsáry, E;Ke, HR;Horváth, EM;Merkely, B;Radovits, T
    Q1
    ANTIOXIDANTS
    2021.
    DOI:10.3390/antiox10081190 (Copy DOI)
    20.
    Chronic swimming training resulted in more relaxed coronary arterioles in male and enhanced vasoconstrictor ability in female rats
    Török, M;Horváth, EM;Monori-Kiss, A;Pál, É;Gerszi, D;Merkely, P;Sayour, AA;Mátyás, C;Oláh, A;Radovits, T;Merkely, B;Acs, N;Nádasy, GL;Várbíró, S
    Q2
    JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS
    2021.
    DOI:10.23736/S0022-4707.20.11316-1 (Copy DOI)
    21.
    Network analysis of the left anterior descending coronary arteries in swim-trained rats by an in situ video microscopic technique
    Török, M;Merkely, P;Monori-Kiss, A;Horváth, EM;Sziva, RE;Péterffy, B;Jósvai, A;Sayour, AA;Oláh, A;Radovits, T;Merkely, B;Acs, N;Nádasy, GL;Várbíró, S
    D1
    BIOLOGY OF SEX DIFFERENCES
    2021.
    DOI:10.1186/s13293-021-00379-y (Copy DOI)
    22.
    Aspirin Reduces Ischemia-Reperfusion Injury Induced Endothelial Cell Damage of Arterial Grafts in a Rodent Model
    Veres, G;Benke, K;Stengl, R;Bai, Y;Stark, KA;Sayour, AA;Radovits, T;Loganathan, S;Korkmaz-Icöz, S;Karck, M;Szabó, G
    D1
    ANTIOXIDANTS
    2022.
    DOI:10.3390/antiox11020177 (Copy DOI)
    23.
    Preservation solution Custodiol containing human alpha-1-antitrypsin improves graft recovery after prolonged cold ischemic storage in a rat model of heart transplantation
    Korkmaz-Icöz, S;Abulizi, S;Li, KS;Korkmaz, B;Georgevici, AI;Sayour, AA;Loganathan, S;Canoglu, H;Karck, M;Szabo, G
    Q1
    FRONTIERS IN IMMUNOLOGY
    2023.
    DOI:10.3389/fimmu.2023.1155343 (Copy DOI)
    Semmelweis University authors: Georgevici, Adrian-Iustin, Sayour, Alex Ali,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Cardiovascular Center,
    24.
    Effects of SGLT2 Inhibitors beyond Glycemic Control-Focus on Myocardial SGLT1
    Sayour, AA;Ruppert, M;Oláh, A;Benke, K;Barta, BA;Zsáry, E;Merkely, B;Radovits, T
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2021.
    DOI:10.3390/ijms22189852 (Copy DOI)
    25.
    Pressure overload-induced systolic heart failure is associated with characteristic myocardial microRNA expression signature and post-transcriptional gene regulation in male rats
    Ruppert, M;Korkmaz-Icöz, S;Benczik, B;Agg, B;Nagy, D;Bálint, T;Sayour, AA;Oláh, A;Barta, BA;Benke, K;Ferdinandy, P;Karck, M;Merkely, B;Radovits, T;Szabó, G
    D1
    SCIENTIFIC REPORTS
    2023.
    DOI:10.1038/s41598-023-43171-1 (Copy DOI)
    26.
    Sex-related differences of early cardiac functional and proteomic alterations in a rat model of myocardial ischemia
    Barta, BA;Ruppert, M;Fröhlich, KE;Cosenza-Contreras, M;Oláh, A;Sayour, AA;Kovács, K;Karvaly, GB;Biniossek, M;Merkely, B;Schilling, O;Radovits, T
    D1
    JOURNAL OF TRANSLATIONAL MEDICINE
    2021.
    DOI:10.1186/s12967-021-03164-y (Copy DOI)
    27.
    In a rat model of bypass DuraGraft ameliorates endothelial dysfunction of arterial grafts
    Lian, S;Loganathan, S;Mayer, T;Kraft, P;Sayour, AA;Georgevici, AI;Veres, G;Karck, M;Szabó, G;Korkmaz-Icöz, S
    Q1
    SCIENTIFIC REPORTS
    2024.
    DOI:10.1038/s41598-024-66056-3 (Copy DOI)
    28.
    A Comparative Investigation of the Pulmonary Vasodilating Effects of Inhaled NO Gas Therapy and Inhalation of a New Drug Formulation Containing a NO Donor Metabolite (SIN-1A)
    Olah, A;Barta, BA;Ruppert, M;Sayour, AA;Nagy, D;Bálint, T;Nagy, GV;Puskás, I;Szente, L;Szocs, L;Sohajda, T;Zima, E;Merkely, B;Radovits, T
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2024.
    DOI:10.3390/ijms25147981 (Copy DOI)
    29.
    Conditioned Medium from Mesenchymal Stem Cells Alleviates Endothelial Dysfunction of Vascular Grafts Submitted to Ischemia/Reperfusion Injury in 15-Month-Old Rats
    Korkmaz-Icöz, S;Sun, XX;Li, SL;Brlecic, P;Loganathan, S;Ruppert, M;Sayour, AA;Radovits, T;Karck, M;Szabó, G
    Q1
    CELLS
    2021.
    DOI:10.3390/cells10051231 (Copy DOI)
    30.
    Myocardial bridge: morphological factors which influence symptoms
    György, B;Béla, M;Attila, O;Sára, P;Alex, SA;István, S;András, Z;Dávid, B
    Q4
    ORVOSI HETILAP
    2023.
    DOI:10.1556/650.2023.32744 (Copy DOI)
    31.
    Dynamics of exercise training and detraining induced cardiac adaptations
    Oláh, A;Sayour, AA;Ruppert, M;Barta, BA;Merkely, B;Kovács, A;Radovits, T
    Q2
    CURRENT OPINION IN PHYSIOLOGY
    2023.
    DOI:10.1016/j.cophys.2023.100657 (Copy DOI)
    32.
    Bone Marrow Culture-Derived Conditioned Medium Recovers Endothelial Function of Vascular Grafts following In Vitro Ischemia/Reperfusion Injury in Diabetic Rats
    Korkmaz-Icöz, S;Sistori, G;Loganathan, S;Sayour, AA;Brlecic, P;Radovits, T;Brune, M;Karck, M;Szabó, G
    Q2
    STEM CELLS INTERNATIONAL
    2022.
    DOI:10.1155/2022/7019088 (Copy DOI)
    33.
    Morphometric and Functional Evaluation of Nonrenal Vasculature in Female and Male PKD/Mhm (Cy/ plus ) Rats
    Liu, BE;Ma, M;Kraft, P;Mayer, T;Sayour, AA;Bierhoff, K;Clanget, TS;Brune, M;Schaefer, F;Karck, M;Szabó, G;Korkmaz-Icöz, S
    Q2
    KIDNEY & BLOOD PRESSURE RESEARCH
    2026.
    DOI:10.1159/000550553 (Copy DOI)
    Semmelweis University authors: Sayour, Alex Ali,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Cardiovascular Center,
    34.
    Do small-conductance Ca2+-activated K+-channels contribute to ventricular repolarization in human heart failure?
    Mohammed, ASA;Demeter-Haludka, V;Abdelmagid, AAE;Topal, L;Muhammad, N;Mohácsi, G;Paskuj, B;Bitay, G;Kohajda, Z;Benke, K;Sayour, AA;Radovits, T;Bitay, M;Virág, L;Jost, N;Baczkó, I;Varró, A;Merkely, B;Nagy, N
    Q1
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
    2026.
    DOI:10.1152/ajpheart.00540.2025 (Copy DOI)
    35.
    Left-ventricular hypertrophy in 18-month-old donor rat hearts was not associated with graft dysfunction in the early phase of reperfusion after cardiac transplantation-gene expression profiling
    Korkmaz-Icöz, S;Akca, D;Li, SL;Loganathan, S;Brlecic, P;Ruppert, M;Sayour, AA;Simm, A;Brune, M;Radovits, T;Karck, M;Szabó, G
    D1
    GEROSCIENCE
    2021.
    DOI:10.1007/s11357-021-00348-8 (Copy DOI)
    36.
    Metrics of left ventricular active relaxation reflect proteomic myocardial remodelling and reverse remodelling
    Barta, BA;Spiesshofer, S;Ruppert, M;Pinter, N;Brombacher, E;Kreutz, C;Korkmaz-Icoz, S;Oláh, A;Sayour, AA;Szabó, G;Merkely, B;Radovits, T;Schilling, O
    Q2
    ESC HEART FAILURE
    2026.
    DOI:10.1093/eschf/xvag112 (Copy DOI)
    37.
    Atrial fibrillation is not associated with altered left atrial microRNA expression profile in patients with advanced heart failure
    Bálint, T;Ruppert, M;Agg, B;Nagy, D;Pálóczi, K;Szenthe, K;Bánáti, F;Sayour, AA;Oláh, A;Barta, BA;Barallobre-Barreiro, J;Ferdinandy, P;Merkely, B;Radovits, T
    Q1
    HEART RHYTHM
    2026.
    DOI:10.1016/j.hrthm.2025.05.041 (Copy DOI)
    38.
    The sodium-glucose cotransporter-2 inhibitor canagliflozin alleviates endothelial dysfunction in a rat bypass model
    Ma, M;Lian, S;Kraft, P;Mayer, T;Sayour, AA;Karck, M;Szabo, G;Korkmaz-Icoez, S
    D1
    BIOCHEMICAL PHARMACOLOGY
    2026.
    DOI:10.1016/j.bcp.2025.117601 (Copy DOI)
    Semmelweis University authors: Sayour, Alex Ali,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Cardiovascular Center,
    39.
    Long-term exercise training is associated with unique cardiac troponin I phosphorylation pattern and benign myocardial hypertrophy in the right ventricle in an experimental model of exercise-induced myocardial remodelling
    Oláh, A;Bódi, B;Barta, BA;Bottlik, O;Sayour, AA;Ruppert, M;Kolodziejska, KK;Kovács, A;Varga, ZV;Ferdinandy, P;Schilling, O;Papp, Z;Merkely, B;Radovits, T
    Q1
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
    2025.
    DOI:10.1016/j.yjmcc.2025.08.008 (Copy DOI)
    40.
    Cathepsin C inhibition boosts heart transplant function
    Liu, B;Korkmaz, B;Kraft, P;Mayer, T;Sayour, AA;Grundl, MA;Domain, R;Karck, M;Szabó, G;Korkmaz-Icöz, S
    Q4
    ZEITSCHRIFT FUR HERZ THORAX UND GEFASSCHIRURGIE
    2026.
    DOI:10.1007/s00398-026-00768-8 (Copy DOI)
    Semmelweis University authors: Sayour, Alex Ali,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Cardiovascular Center,
    41.
    Inflammasome pathway component expressions in myocardial samples of advanced heart failure patients treated with novel heart failure pharmacotherapies
    Nagy, Dávid; Onódi, Zsófia; Kovács, Andrea; Bálint, Tímea; Horváth, Zoltán; Oláh, Attila; Sayour, Alex Ali; Barta, Bálint András; Ferdinandy, Péter; Radovits, Tamás; Merkely, Béla; Varga, Zoltán; Ruppert, Mihály;
    Q1
    INTERNATIONAL JOURNAL OF CARDIOLOGY 0167-5273 1874-1754
    2026.
    DOI:10.1016/j.ijcard.2026.134686 (Copy DOI)

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