Semmelweis Publications
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    • Sayour, Viktor Nabil Semmelweis University affiliated publications (2020-2025)

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    Number of publications: 22
    1.
    Molecular fingerprints of cardiovascular toxicities of immune checkpoint inhibitors
    Gergely, TG;Drobni, ZD;Sayour, NV;Ferdinandy, P;Varga, ZV
    D1
    BASIC RESEARCH IN CARDIOLOGY
    2025.
    DOI:10.1007/s00395-024-01068-8 (Copy DOI)
    2.
    Characterization of immune checkpoint inhibitor-induced cardiotoxicity reveals interleukin-17A as a driver of cardiac dysfunction after anti-PD-1 treatment
    Gergely, TG;Kucsera, D;Tóth, VE;Kovács, T;Sayour, N;Drobni, ZD;Ruppert, M;Petrovich, B;Agg, B;Onódi, Z;Fekete, N;Pállinger, É;Buzás, E;Yousif, L;Meijers, WC;Radovits, T;Merkely, B;Ferdinandy, P;Varga, ZV
    D1
    BRITISH JOURNAL OF PHARMACOLOGY
    2023.
    DOI:10.1111/bph.15984 (Copy DOI)
    3.
    Heart failure pharmacotherapy and cancer: pathways and pre-clinical/clinical evidence
    Sayour, NV;Paál, AM;Ameri, P;Meijers, WC;Minotti, G;Andreadou, I;Lombardo, A;Camilli, M;Drexel, H;Grove, EL;Dan, GA;Ivanescu, A;Semb, AG;Savarese, G;Dobrev, D;Crea, F;Kaski, JC;de Boer, RA;Ferdinandy, P;Varga, ZV
    D1
    EUROPEAN HEART JOURNAL
    2024.
    DOI:10.1093/eurheartj/ehae105 (Copy DOI)
    4.
    Comparison of mouse models of heart failure with reduced ejection fraction
    Sayour, NV;Gergely, TG;Váradi, B;Tóth, VÉ;Agg, B;Kovács, T;Kucsera, D;Kovácsházi, C;Brenner, GB;Giricz, Z;Ferdinandy, P;Varga, ZV
    Q1
    ESC HEART FAILURE
    2025.
    DOI:10.1002/ehf2.15031 (Copy DOI)
    5.
    NASH triggers cardiometabolic HFpEF in aging mice
    Kucsera, D;Ruppert, M;Sayour, NV;Tóth, VE;Kovács, T;Hegedus, ZI;Onódi, Z;Fábián, A;Kovács, A;Radovits, T;Merkely, B;Pacher, P;Ferdinandy, P;Varga, ZV
    D1
    GEROSCIENCE
    2024.
    DOI:10.1007/s11357-024-01153-9 (Copy DOI)
    6.
    Effects of sex and obesity on immune checkpoint inhibition-related cardiac systolic dysfunction in aged mice
    Sayour, NV;Kucsera, D;Alhaddad, AR;Tóth, VE;Gergely, TG;Kovács, T;Hegedus, ZI;Jakab, ME;Ferdinandy, P;Varga, ZV
    D1
    BASIC RESEARCH IN CARDIOLOGY
    2025.
    DOI:10.1007/s00395-024-01088-4 (Copy DOI)
    7.
    Cardioprotective efficacy of limb remote ischaemic preconditioning in rats: discrepancy between a meta-analysis and a three-centre in vivo study
    Sayour, NV;Brenner, GB;Makkos, A;Kiss, B;Kovácsházi, C;Gergely, TG;Aukrust, SG;Tian, HM;Zenkl, V;Gömöri, K;Szabados, T;Bencsik, P;Heinen, A;Schulz, R;Baxter, GF;Zuurbier, CJ;Vokó, Z;Ferdinandy, P;Giricz, Z
    D1
    CARDIOVASCULAR RESEARCH
    2023.
    DOI:10.1093/cvr/cvad024 (Copy DOI)
    8.
    Reduced circulating CD63+ extracellular vesicle levels associate with atherosclerosis in hypercholesterolaemic mice and humans
    Kestecher, BM;Németh, K;Ghosal, S;Sayour, NV;Gergely, TG;Bodnár, BR;Försönits, AI;Sódar, BW;Oesterreicher, J;Holnthoner, W;Varga, ZV;Giricz, Z;Ferdinandy, P;Buzás, EI;Osteikoetxea, X
    D1
    CARDIOVASCULAR DIABETOLOGY
    2024.
    DOI:10.1186/s12933-024-02459-w (Copy DOI)
    9.
    Tirzepatide, a dual GIP/GLP1-receptor co-agonist preserves cardiac function and improves survival in angiotensin II-induced heart failure model in mice: comparison to liraglutide
    Hegedüs, ZI;Jakab, ME;Gergely, TG;Sayour, NV;Kovács, A;Antal, S;Kovács, T;Ferdinandy, P;Varga, ZV;Tóth, VE
    D1
    CARDIOVASCULAR DIABETOLOGY
    2025.
    DOI:10.1186/s12933-025-02806-5 (Copy DOI)
    10.
    IL-1β neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH
    Kucsera, D;Tóth, VE;Sayour, NV;Kovács, T;Gergely, TG;Ruppert, M;Radovits, T;Fábián, A;Kovács, A;Merkely, B;Ferdinandy, P;Varga, ZV
    D1
    SCIENTIFIC REPORTS
    2023.
    DOI:10.1038/s41598-022-26896-3 (Copy DOI)
    11.
    Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles
    Kovácsházi, C;Hambalkó, S;Sayour, NV;Gergely, TG;Brenner, GB;Pelyhe, C;Kapui, D;Weber, BY;Hültenschmidt, AL;Pállinger, E;Buzás, EI;Zolcsák, A;Kiss, B;Bozó, T;Csányi, C;Kosa, N;Kellermayer, M;Farkas, R;Karvaly, GB;Wynne, K;Matallanas, D;Ferdinandy, P;Giricz, Z
    Q1
    SCIENTIFIC REPORTS
    2024.
    DOI:10.1038/s41598-024-62689-6 (Copy DOI)
    12.
    Droplet Digital PCR Is a Novel Screening Method Identifying Potential Cardiac G-Protein-Coupled Receptors as Candidate Pharmacological Targets in a Rat Model of Pressure-Overload-Induced Cardiac Dysfunction
    Sayour, NV;Tóth, VÉ;Nagy, RN;Vörös, I;Gergely, TG;Onódi, Z;Nagy, N;Bödör, C;Váradi, B;Ruppert, M;Radovits, T;Bleckwedel, F;Zelarayán, LC;Pacher, P;Agg, B;Görbe, A;Ferdinandy, P;Varga, ZV
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2023.
    DOI:10.3390/ijms241813826 (Copy DOI)
    13.
    Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Gottingen Minipigs and Landrace Pigs
    Brenner, GB;Giricz, Z;Garamvölgyi, R;Makkos, A;Onódi, Z;Sayour, N;Gergely, TG;Baranyai, T;Petneházy, Ö;Korösi, D;Szabó, GP;Vago, H;Dohy, Z;Czimbalmos, C;Merkely, B;Boldin-Adamsky, S;Feinstein, E;Horváth, IG;Ferdinandy, P
    Q2
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
    2021.
    DOI:10.3791/61901 (Copy DOI)
    14.
    Hidden Cardiotoxicity of Rofecoxib Can be Revealed in Experimental Models of Ischemia/Reperfusion
    Brenner, GB;Makkos, A;Nagy, CT;Onódi, Z;Sayour, NV;Gergely, TG;Kiss, B;Görbe, A;Sághy, É;Zádori, ZS;Lázár, B;Baranyai, T;Varga, RS;Husti, Z;Varró, A;Tóthfalusi, L;Schulz, R;Baczkó, I;Giricz, Z;Ferdinandy, P
    Q1
    CELLS
    2020.
    DOI:10.3390/cells9030551 (Copy DOI)
    15.
    Rosiglitazone Does Not Show Major Hidden Cardiotoxicity in Models of Ischemia/Reperfusion but Abolishes Ischemic Preconditioning-Induced Antiarrhythmic Effects in Rats In Vivo
    Weber, BY;Brenner, GB;Kiss, B;Gergely, TG;Sayour, N;Tian, HM;Makkos, A;Görbe, A;Ferdinandy, P;Giricz, Z
    Q1
    PHARMACEUTICALS
    2022.
    DOI:10.3390/ph15091055 (Copy DOI)
    16.
    Helium Conditioning Increases Cardiac Fibroblast Migration Which Effect Is Not Propagated via Soluble Factors or Extracellular Vesicles
    Jelemensky, M;Kovácsházi, C;Ferenczyová, K;Hofbauerová, M;Kiss, B;Pállinger, É;Kittel, A;Sayour, VN;Görbe, A;Pelyhe, C;Hambalkó, S;Kindernay, L;Barancík, M;Ferdinandy, P;Barteková, M;Giricz, Z
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2021.
    DOI:10.3390/ijms221910504 (Copy DOI)
    17.
    Effects of Bempedoic Acid in Acute Myocardial Infarction in Rats: No Cardioprotection and No Hidden Cardiotoxicity
    Gergely, TG;Brenner, GB;Nagy, RN;Sayour, NV;Makkos, A;Kovácsházi, C;Tian, HM;Schulz, R;Giricz, Z;Görbe, A;Ferdinandy, P
    D1
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
    2023.
    DOI:10.3390/ijms24021585 (Copy DOI)
    18.
    CardiLect: A combined cross-species lectin histochemistry protocol for the automated analysis of cardiac remodelling
    Gergely, TG;Kovács, T;Kovács, A;Tóth, VE;Sayour, NV;Mórotz, GM;Kovácsházi, C;Brenner, GB;Onódi, Z;Enyedi, B;Máthé, D;Leszek, P;Giricz, Z;Ferdinandy, P;Varga, ZV
    Q1
    ESC HEART FAILURE
    2025.
    DOI:10.1002/ehf2.15155 (Copy DOI)
    19.
    Unlocking the power of immune checkpoint inhibitors: Targeting YAP1 reduces anti-PD1 resistance in skin cutaneous melanoma
    Kovács, SA;Kovács, T;Lánczky, A;Paál, A;Hegedús, ZI;Sayour, NV;Szabó, L;Kovács, A;Bianchini, G;Ferdinandy, P;Ocana, A;Varga, ZV;Fekete, JT;Gyorffy, B
    D1
    BRITISH JOURNAL OF PHARMACOLOGY
    2025.
    DOI:10.1111/bph.70052 (Copy DOI)
    20.
    Microgliosis, neuronal death, minor behavioral abnormalities and reduced endurance performance in alpha-ketoglutarate dehydrogenase complex deficient mice
    Kokas, M;Budai, A;Kádár, A;Mozaffaritabar, S;Zhou, L;Téglás, T;Orova, RS;Gáspár, D;Németh, K;Toth, DM;Sayour, N;Kovácsházi, C;Xue, AD;Szatmári, RZ;Törocsik, B;Máthé, D;Kovács, N;Szigeti, K;Nagy, P;Szatmári, I;Fekete, C;Arányi, T;Varga, ZV;Ferdinandy, P;Radák, Z;Kozlov, A;Tretter, L;Komlódi, T;Ambrus, A
    D1
    REDOX BIOLOGY
    2025.
    DOI:10.1016/j.redox.2025.103743 (Copy DOI)
    Semmelweis University authors: Kokas, Márton, Budai, András, Kádár, Andrea, Orova, Rebeka Sára, Németh , Kristóf, Tóth, Dániel Márton, Sayour, Viktor Nabil, Kovácsházi, Csenger, Xue, Andrea, Törőcsik, Beáta, Máthé, Domokos, Stelczerné Kovács, Noémi, Szigeti, Krisztián, Szatmári, Ildikó, Arányi, Tamás, Varga, Zoltán, Ferdinandy, Péter, Radák, Zsolt, Tretter, László, Komlódi, Tímea, Ambrus, Attila,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Departmnet of Biophysics and Radiation Biology, Biokémiai és Molekuláris Biológiai Intézet, Biokémiai Tanszék, Molekuláris Biológiai Tanszék, Department of Pharmacology and Pharmacotherapy, Patológiai, Igazságügyi és Biztosítási Orvostani Intézet, Department of Pediatrics, Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket), Centre for Pharmacology and Pharmaceutical Research Development,
    21.
    Characteristics and outcomes of patients with heart failure and history of malignancy: Data from Swedish Heart Failure Registry and the National Cancer Register
    Ameri, P;Costa, P;Benson, L;Stolfo, D;Sayour, NV;Ljungman, C;Butler, J;Anker, SD;Girerd, N;Keramida, K;Filippatos, G;Lund, LH;Lindberg, F;Savarese, G
    D1
    EUROPEAN JOURNAL OF HEART FAILURE
    2025.
    DOI:10.1002/ejhf.3775 (Copy DOI)
    Semmelweis University authors: Sayour, Viktor Nabil,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Pharmacology and Pharmacotherapy,
    22.
    Framingham risk score associates with incident cancer and heart failure
    van, den Berg Pieter F.; Yousif, Laura I; Koop, Yvonne; Unlu, Ezgi Hatip; Asik, Melis; van, Essen Bart J.; Damman, Kevin; Voors, Adriaan A.; Sayour, Nabil V; Kok, Thomas F.; Yang, Yiqian; Kardys, Isabella; Bakker, Stephan J. L.; van, der Vegt Bert; Suthahar, Navin; de, Boer Rudolf A.; Meijers, Wouter C.;
    D1
    EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY 2047-4873 2047-4881
    2025.
    DOI:10.1093/eurjpc/zwaf618 (Copy DOI)
    Semmelweis University authors: Sayour, Viktor Nabil,
    Semmelweis University departments: Semmelweis University, Faculty of Medicine, Department of Pharmacology and Pharmacotherapy,

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